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SGSH Protein (Myc-DYKDDDDK Tag)

SGSH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732936
  • Target See all SGSH Proteins
    SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SGSH protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Sulphamidase / SGSH protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SGSH Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
    Alternative Name
    Sulphamidase,sgsh (SGSH Products)
    Synonyms
    HSS Protein, MPS3A Protein, SFMD Protein, 4632406A19Rik Protein, N-sulfoglucosamine sulfohydrolase Protein, N-sulfoglucosamine sulfohydrolase (sulfamidase) Protein, SGSH Protein, Sgsh Protein
    Background
    This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
    Molecular Weight
    54.6 kDa
    NCBI Accession
    NP_000190
    Pathways
    Glycosaminoglycan Metabolic Process
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