TLE3 Protein (DYKDDDDK Tag)
Quick Overview for TLE3 Protein (DYKDDDDK Tag) (ABIN2733814)
Target
Protein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TLE3 protein is labelled with DYKDDDDK Tag.
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Characteristics
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- Recombinant human TLE3 (full length, C-term DDK tag, transcript variant 1) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))
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Alternative Name
- Tle3
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Background
- This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Molecular Weight
- 83.4 kDa
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NCBI Accession
- NP_005069
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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