TLE3 Protein (GST tag)

Catalog No. ABIN7317305

Product Details

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TLE3 protein is labelled with GST tag.

Purpose: Recombinant Human TLE3 Protein (aa 484-772, GST Tag)

Sequence: Ser 484-Tyr 772

Characteristics: A DNA sequence encoding the N-terminal fragment of human TLE3 (Q04726-1) (Ser 484-Tyr 772) was fused with the GST tag at the N-terminus.

Purity: > 78 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.15M NaCl, 5 mM GSH, pH 7.5

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Alternative Name: TLE3 (TLE3 Products)

Synonyms: TLE3 Protein, ESG Protein, ESG1 Protein, Xesg1 Protein, esg2 Protein, esg3 Protein, grg2 Protein, grg3 Protein, hst18976 Protein, tle3 Protein, xgrg3 Protein, ESG3 Protein, GRG3 Protein, HsT18976 Protein, Esp3 Protein, 2610103N05Rik Protein, Grg3a Protein, Grg3b Protein, mKIAA1547 Protein, transducin like enhancer of split 3 Protein, transducin like enhancer of split 2 Protein, transducin-like enhancer of split 3 Protein, TLE3 Protein, tle2 Protein, Tle3 Protein

Background:

Background: Immunoglobulin superfamily member 11(IGSF11) are expressed on the plasma membrane in the tesis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to over expressed in colorectal cancers and hepatocellular carcinomas as well as intestinal-type gastric cancers compared to their corresponding non- cancerous tissues. The IGSF11 has also been found expressed abundantly in testis and ovary and the IGSF11 can be used as a candidate of cancer-testis antigen.

Synonym: ESG,ESG3,GRG3,HsT18976

Molecular Weight: 58.5 kDa

Pathways: SARS-CoV-2 Protein Interactome