TMEM27 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733890

Recombinant TMEM27 protein expressed in HEK-293 Cells.

Quick Overview for TMEM27 Protein (Myc-DYKDDDDK Tag) (ABIN2733890)

Target: TMEM27 (Transmembrane Protein 27 (TMEM27))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This TMEM27 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human TMEM27 / Collectrin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TMEM27 (Transmembrane Protein 27 (TMEM27))

Alternative Name: Tmem27,collectrin

Background: This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells.

Molecular Weight: 23.5 kDa

NCBI Accession: NP_065716