TMEM27 Protein (Fc Tag)
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- Target See all TMEM27 Proteins
- TMEM27 (Transmembrane Protein 27 (TMEM27))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TMEM27 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human TMEM27 Protein (Fc Tag)
- Sequence
- Met 1-Pro141
- Characteristics
- A DNA sequence encoding the human TMEM27 (Q9HBJ8) (Met1-Pro141) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TMEM27 Protein
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Transmembrane Protein 27 (TMEM27) (AA 15-141) protein (His tag)
TMEM27 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Transmembrane Protein 27 (TMEM27) (AA 1-222) protein (GST tag)TMEM27 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TMEM27 (Transmembrane Protein 27 (TMEM27))
- Alternative Name
- TMEM27 (TMEM27 Products)
- Synonyms
- NX17 Protein, nx-17 Protein, MGC68634 Protein, collectrin Protein, tmem27 Protein, NX-17 Protein, 0610008J07Rik Protein, Nx17 Protein, transmembrane protein 27 L homeolog Protein, si:dkey-194e6.1 Protein, transmembrane protein 27 Protein, tmem27.L Protein, si:dkey-194e6.1 Protein, TMEM27 Protein, tmem27 Protein, Tmem27 Protein
- Background
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Background: TMEM27 is a membrane protein. It has been proposed as a beta cell mass biomarker since it is cleaved and shed by pancreatic beta cells. Overexpression of TMEM27 leads to increased thymidine incorporation, whereas silencing of Tmem27 using RNAi results in a reduction of cell replication. Furthermore, transgenic mice with increased expression of Tmem27 in pancreatic beta cells exhibit increased beta cell mass. TMEM27 is also important for trafficking amino acid transporters to the apical brush border of proximal tubules.
Synonym: NX-17,NX17
- Molecular Weight
- 41.4 kDa
- UniProt
- Q9HBJ8
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