USP8 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for USP8 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2735145)
Target
See all USP8 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This USP8 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human USP8 / UBPY (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Ubiquitin Specific Peptidase 8 (USP8) (AA 886-1096) protein (His-IF2DI Tag)
USP8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)USP8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)USP8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- USP8 (Ubiquitin Specific Peptidase 8 (USP8))
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Alternative Name
- Usp8,ubpy
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Background
- This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.
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Molecular Weight
- 127.3 kDa
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NCBI Accession
- NP_005145
Target
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