WWP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
Quick Overview for WWP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2735643)
Target
See all WWP2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 3
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Purification tag / Conjugate
- This WWP2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
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Background
- This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.
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Molecular Weight
- 35.1 kDa
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NCBI Accession
- NP_955455
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Pathways
- Negative Regulation of Transporter Activity
Target
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