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PLGF Protein

PGF Origin: Human Host: Insect cells (Sf9) Recombinant >95 % (SDS-PAGE) SDS Active
Catalog No. ABIN2745803
  • Target See all PLGF (PGF) Proteins
    PLGF (PGF) (Placenta Growth Factor (PGF))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 23
    • 9
    • 4
    • 3
    • 1
    Human
    Source
    • 14
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Insect cells (Sf9)
    Application
    SDS-PAGE (SDS)
    Cross-Reactivity
    Human
    Characteristics
    Human PLGF (131aa).
    Purity
    >95 % (SDS-PAGE)
    Top Product
    Discover our top product PGF Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.
    Concentration
    Lot specific
    Buffer
    Lyophilized.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Target
    PLGF (PGF) (Placenta Growth Factor (PGF))
    Alternative Name
    PLGF (PGF Products)
    Synonyms
    D12S1900 Protein, PGFL Protein, PLGF Protein, PlGF-2 Protein, SHGC-10760 Protein, AI854365 Protein, PIGF Protein, Plgf Protein, PlGF Protein, placental growth factor Protein, placenta growth factor Protein, PGF Protein, Pgf Protein, PLGF Protein
    Background
    Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.
    Molecular Weight
    ~34kDa (dimer)
    UniProt
    P49763
    Pathways
    VEGFR1 Specific Signals
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