VEGFC Protein (His tag)
Quick Overview for VEGFC Protein (His tag) (ABIN2746013)
Target
See all VEGFC ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This VEGFC protein is labelled with His tag.
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Purpose
- VEGF-C (human) (rec.) (His)
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Cross-Reactivity
- Human
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Characteristics
- Human VEGF-C (115aa) is fused at the C-terminus to a His-tag.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Soluble in water and most aqueous buffers. Reconstitute in PBS or medium to a concentration not lower than 50 μg/mL.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.
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Expiry Date
- 6 months
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- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
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Alternative Name
- VEGF-C
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Background
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Vascular Endothelial Growth Factor C, VRP, Flt4-L
VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
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Molecular Weight
- ~18-24kDa
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UniProt
- P49767
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Pathways
- RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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