IL-8 Protein
Quick Overview for IL-8 Protein (ABIN2830213)
Target
See all IL-8 (IL8) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Sequence
- AVLPRSAKEL RCECIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE PWVQRVVEKF VKRAENQNP
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Characteristics
- Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 0.5-5.0 ng/mL.
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Sterility
- 0.2 μm filtered
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- IL-8 (IL8) (Interleukin 8 (IL8))
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Alternative Name
- CXCL8
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Background
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Relevance: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity). {ECO:0000250}.
Synonyms: IL-8, Chemokine C-X-C motif, ligand 8 -
Molecular Weight
- 9.14kDa
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UniProt
- P67813
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Pathways
- TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
Target
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