IL12A Protein
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- Target See all IL12A Proteins
- IL12A (Interleukin 12 alpha (IL12A))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Mammalian Cells
- Application
- Functional Studies (Func)
- Sequence
- p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS p40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS
- Characteristics
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using PHA-activated human T lymphoblasts is less than 0.05 ng/mL, corresponding to a specific activity of ＞ 2.0 x 107 IU/mg.
- Purity
- >95 % as determined by SDS-PAGE and HPLC.
- Sterility
- 0.2 μm filtered
- Top Product
- Discover our top product IL12A Protein
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Interleukin 12 alpha (IL12A) (AA 57-253) protein
IL12A Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Interleukin 12 alpha (IL12A) (AA 144-253) protein (GST tag)IL12A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 12 alpha (IL12A) (AA 23-219) protein (His tag)Crystallography grade IL12A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 alpha (IL12A) (AA 23-215) protein (His tag)Crystallography grade IL12A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- IL12A (Interleukin 12 alpha (IL12A))
- Alternative Name
- IL12A (IL12A Products)
- Synonyms
- CLMF Protein, IL-12A Protein, NFSK Protein, NKSF1 Protein, P35 Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p35 Protein, Il-12 p35 Protein, IL12p40 Protein, IL12 Protein, IL-12 p35 Protein, interleukin 12A Protein, interleukin 12B Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12A Protein, IL12B Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein
- Background
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Relevance: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Synonyms: IL-12A, CLMF p35, IL-12 subunit p35, NK cell stimulatory factor chain 1, NKSF1 - Molecular Weight
- 75 kDa
- UniProt
- P29459
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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