FCGR3A Protein (AA 32-215) (His tag)
Quick Overview for FCGR3A Protein (AA 32-215) (His tag) (ABIN2870739)
Target
See all FCGR3A ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 32-215
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Purification tag / Conjugate
- This FCGR3A protein is labelled with His tag.
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Brand
- MABSol®
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Sequence
- AA 32-215
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Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.95 kDa. The protein migrates as 36-45 kDa under reducing (R) condition (SDS-PAGE).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-208) protein (His-Avi Tag,Biotin)
FCGR3A Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-208) protein (His-Avi Tag)FCGR3A Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-254) protein (GST tag)FCGR3A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-208), (F176V) (Active) protein (His tag)FCGR3A Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (His tag)FCGR3A Origin: Human Host: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (Biotin,His-Avi Tag)FCGR3A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) protein (His tag)FCGR3A Origin: Cynomolgus Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (His tag,AVI tag)FCGR3A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (His tag)FCGR3A Origin: Rat Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-206) protein (His tag)FCGR3A Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
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Alternative Name
- Fc gamma RIIIA / CD16a
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Background
- CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
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Molecular Weight
- 23.0 kDa
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UniProt
- Q5D5I8
Target
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