BTN1A1 Protein (AA 27-242) (Fc Tag)

Catalog No. ABIN4949082

This Recombinant BTN1A1 protein is produced in HEK-293 Cells.

Quick Overview for BTN1A1 Protein (AA 27-242) (Fc Tag) (ABIN4949082)

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Functional Studies (Func)

Purity: >95 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 27-242

Purification tag / Conjugate: This BTN1A1 protein is labelled with Fc Tag.

Sequence: AA 27-242

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE).

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Alternative Name: BTN1A1

Background: Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Molecular Weight: 50.6 kDa

Pathways: Activated T Cell Proliferation