C8G Protein (AA 21-202) (His-SUMO Tag)

Catalog No. ABIN5709171

Product Details

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Protein Type: Recombinant

Protein Characteristics: AA 21-202

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This C8G protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: QKPQRPRRPA SPISTIQPKA NFDAQQFAGT WLLVAVGSAC RFLQEQGHRA EATTLHVAPQ GTAMAVSTFR KLDGICWQVR QLYGDTGVLG RFLLQARGAR GAVNVVVAET DYQSFAVLYL ERAGQLSVKL YARSLPVSDS VLSGFEQRVQ EAHLTEDQIF YFPKYGFCEA ADQFHVLDEV RR

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Alternative Name: CO8G (C8G Products)

Synonyms: C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein

Background: C8 is a constituent of the mbrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit ses to be able to bind retinol.

Molecular Weight: 36.29 kDa

UniProt: P07360

Pathways: Complement System