C8G Protein (His tag)
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- Target See all C8G Proteins
- C8G (Complement Component 8, gamma Polypeptide (C8G))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This C8G protein is labelled with His tag.
- Purpose
- Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag)
- Sequence
- Gln21-Arg202
- Characteristics
- Recombinant Human Complement component C8 gamma chain is produced by our E.coli expression system and the target gene encoding Gln21-Arg202 is expressed with a 6His tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product C8G Protein
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Complement Component 8, gamma Polypeptide (C8G) (AA 21-202) protein (His tag)
C8G Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Complement Component 8, gamma Polypeptide (C8G) (AA 21-202) protein (His tag)Crystallography grade C8G Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Complement Component 8, gamma Polypeptide (C8G) (AA 21-202) protein (His-SUMO Tag)C8G Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- C8G (Complement Component 8, gamma Polypeptide (C8G))
- Alternative Name
- Complement Component C8 Gamma Chain/C8G (C8G Products)
- Synonyms
- C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein
- Background
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Background: Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
Synonym: Complement component C8 gamma chain,C8G
- Molecular Weight
- 22.6 kDa
- UniProt
- P07360
- Pathways
- Complement System
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