HVEM Protein (AA 39-202) (His tag)
Quick Overview for HVEM Protein (AA 39-202) (His tag) (ABIN5853390)
Target
See all HVEM (TNFRSF14) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 39-202
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Purification tag / Conjugate
- This HVEM protein is labelled with His tag.
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Sequence
- MGSSHHHHHH SSGLVPRGSH MGSLPSCKED EYPVGSECCP KCSPGYRVKE ACGELTGTVC EPCPPGTYIA HLNGLSKCLQ CQMCDPAMGL RASRNCSRTE NAVCGCSPGH FCIVQDGDHC AACRAYATSS PGQRVQKGGT ESQDTLCQNC PPGTFSPNGT LEECQHQTKC SWLVTKAGAG TSSSHWV
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.1M NaCl
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
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Alternative Name
- TNFRSF14
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Target Type
- Viral Protein
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Background
- TNFRSF14, as known as herpesvirus entry mediator (HVEM), is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Recombinant human TNFRSF14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
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Molecular Weight
- 19.7 kDa(187aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_003811
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UniProt
- Q92956
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Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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