IL5RA Protein (AA 18-339) (His tag)
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- Target See all IL5RA Proteins
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 18-339
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This IL5RA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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DLLNHKKFLL LPPVNFTIKA TGLAQVLLHW DPNPDQEQRH VDLEYHVKIN APQEDEYDTR KTESKCVTPL HEGFAASVRT ILKSSHTTLA SSWVSAELKA PPGSPGTSVT NLTCTTHTVV SSHTHLRPYQ VSLRCTWLVG KDAPEDTQYF LYYRFGVLTE KCQEYSRDAL NRNTACWFPR TFINSKGFEQ LAVHINGSSK RAAIKPFDQL FSPLAIDQVN PPRNVTVEIE SNSLYIQWEK PLSAFPDHCF NYELKIYNTK NGHIQKEKLI ANKFISKIDD VSTYSIQVRA AVSSPCRMPG RWGEWSQPIY VGKERKSLVE WH
- Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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- Discover our top product IL5RA Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- Alternative Name
- IL-5R alpha/IL5RA (IL5RA Products)
- Background
- Il5ra, also known as interleukin-5 receptor subunit alpha, is known to regulate the development and function of eosinophils. This protein is a therapeutic target for hypereosinophilic diseases including allergic inflammations and asthma. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. Recombinant mouse Il5ra, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 37.8 kDa (330aa)
- NCBI Accession
- NP_032396
- UniProt
- P21183
- Pathways
- JAK-STAT Signaling
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