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IL5RA Protein (AA 18-339) (His tag)

IL5RA Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Catalog No. ABIN5854571
  • Target See all IL5RA Proteins
    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-339
    Origin
    • 14
    • 5
    Mouse
    Source
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This IL5RA protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    DLLNHKKFLL LPPVNFTIKA TGLAQVLLHW DPNPDQEQRH VDLEYHVKIN APQEDEYDTR KTESKCVTPL HEGFAASVRT ILKSSHTTLA SSWVSAELKA PPGSPGTSVT NLTCTTHTVV SSHTHLRPYQ VSLRCTWLVG KDAPEDTQYF LYYRFGVLTE KCQEYSRDAL NRNTACWFPR TFINSKGFEQ LAVHINGSSK RAAIKPFDQL FSPLAIDQVN PPRNVTVEIE SNSLYIQWEK PLSAFPDHCF NYELKIYNTK NGHIQKEKLI ANKFISKIDD VSTYSIQVRA AVSSPCRMPG RWGEWSQPIY VGKERKSLVE WH
    Purity
    > 90% by SDS-PAGE
    Endotoxin Level
    < 1 EU per 1ug of protein (determined by LAL method)
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target
    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
    Alternative Name
    IL-5R alpha/IL5RA (IL5RA Products)
    Background
    Il5ra, also known as interleukin-5 receptor subunit alpha, is known to regulate the development and function of eosinophils. This protein is a therapeutic target for hypereosinophilic diseases including allergic inflammations and asthma. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. Recombinant mouse Il5ra, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    37.8 kDa (330aa)
    NCBI Accession
    NP_032396
    UniProt
    P21183
    Pathways
    JAK-STAT Signaling
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