CRLF2 Protein (AA 23-231) (His tag)
Quick Overview for CRLF2 Protein (AA 23-231) (His tag) (ABIN5854751)
Target
See all CRLF2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 23-231
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Purification tag / Conjugate
- This CRLF2 protein is labelled with His tag.
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Sequence
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QGGAAEG VQIQIIYFNL ETVQVTWNAS KYSRTNLTFH YRFNGDEAYD QCTNYLLQEG HTSGCLLDAE QRDDILYFSI RNGTHPVFTA SRWMVYYLKP SSPKHVRFSW HQDAVTVTCS DLSYGDLLYE VQYRSPFDTE WQSKQENTCN VTIEGLDAEK CYSFWVRVKA MEDVYGPDTY PSDWSEVTCW QRGEIRDACA ETPTPPKPKL SK -
Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) protein (Fc Tag)
CRLF2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) protein (His tag)CRLF2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) protein (His tag)CRLF2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) (Active) protein (Fc Tag)CRLF2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytokine Receptor-Like Factor 2 (CRLF2) (Active) protein (Fc Tag)CRLF2 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) protein (His tag)CRLF2 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Cytokine Receptor-Like Factor 2 (CRLF2) protein (His tag)CRLF2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cytokine Receptor-Like Factor 2 (CRLF2) protein (Fc Tag)CRLF2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cytokine Receptor-Like Factor 2 (CRLF2) protein (His tag)CRLF2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
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Alternative Name
- CRLF2
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Background
- CRLF2, also known as cytokine receptor-like factor 2 isoform 1, is a receptor for thymic stromal lymphopoietin. It is proposed to signal through a heterodimeric receptor complex that consists of a new member of the hemopoietin family termed CRLF2 and the IL-7R alpha-chain. The protein induces phosphorylation of Stat3 and Stat5 also activate JAK2 pathways. CRLF2 and IL-7R alpha are principally coexpressed on monocytes and dendritic cell populations and to a much lesser extent of various lymphoid cells. Recombinant human CRLF2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 25.2 kDa (218aa)
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NCBI Accession
- NP_071431
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UniProt
- Q9HC73
Target
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