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TXN Protein (AA 2-105, full length) (GST tag)

This Recombinant TXN protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7479607
$553.08
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Quick Overview for TXN Protein (AA 2-105, full length) (GST tag) (ABIN7479607)

Target

See all TXN Proteins
TXN (Thioredoxin (TXN))

Protein Type

Recombinant

Origin

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Human

Source

  • 16
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Escherichia coli (E. coli)

Application

SDS-PAGE (SDS), Western Blotting (WB), ELISA

Purity

95 %
  • Protein Characteristics

    AA 2-105, full length

    Purification tag / Conjugate

    This TXN protein is labelled with GST tag.

    Sequence

    VKQIESKTAF QEALDAAGDK LVVVDFSATW CGPCKMIKPF FHSLSEKYSN VIFLEVDVDD CQDVASECEV KCMPTFQFFK KGQKVGEFSG ANKEKLEATI NELV
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS buffer, 20mM GSH

    Storage

    4 °C
  • Target

    TXN (Thioredoxin (TXN))

    Alternative Name

    Thioredoxin

    Background

    Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Ref.16 Ref.18 Ref.19 Ref.21 Ref.24 ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). Synonyms: Short name=Trx Alternative name(s): ATL-derived factor Short name=ADF Surface-associated sulphydryl protein Short name=SASP.

    Molecular Weight

    39 kD

    NCBI Accession

    NM_003329

    UniProt

    P10599

    Pathways

    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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