TXN Protein (AA 2-105, full length) (GST tag)
Quick Overview for TXN Protein (AA 2-105, full length) (GST tag) (ABIN7479607)
Target
See all TXN ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 2-105, full length
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Purification tag / Conjugate
- This TXN protein is labelled with GST tag.
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Sequence
- VKQIESKTAF QEALDAAGDK LVVVDFSATW CGPCKMIKPF FHSLSEKYSN VIFLEVDVDD CQDVASECEV KCMPTFQFFK KGQKVGEFSG ANKEKLEATI NELV
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS buffer, 20mM GSH
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Storage
- 4 °C
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- TXN (Thioredoxin (TXN))
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Alternative Name
- Thioredoxin
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Background
- Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Ref.16 Ref.18 Ref.19 Ref.21 Ref.24 ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). Synonyms: Short name=Trx Alternative name(s): ATL-derived factor Short name=ADF Surface-associated sulphydryl protein Short name=SASP.
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Molecular Weight
- 39 kD
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NCBI Accession
- NM_003329
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UniProt
- P10599
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Pathways
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
Target
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