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TXN Protein (AA 2-105, full length) (GST tag)

TXN Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % SDS, WB, ELISA
Catalog No. ABIN7479607
  • Target See all TXN Proteins
    TXN (Thioredoxin (TXN))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 2-105, full length
    Origin
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 16
    • 14
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TXN protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS), Western Blotting (WB), ELISA
    Sequence
    VKQIESKTAF QEALDAAGDK LVVVDFSATW CGPCKMIKPF FHSLSEKYSN VIFLEVDVDD CQDVASECEV KCMPTFQFFK KGQKVGEFSG ANKEKLEATI NELV
    Purity
    95 %
    Top Product
    Discover our top product TXN Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS buffer, 20mM GSH
    Storage
    4 °C
  • Target
    TXN (Thioredoxin (TXN))
    Alternative Name
    Thioredoxin (TXN Products)
    Synonyms
    TRDX Protein, TRX Protein, TRX1 Protein, ADF Protein, AW550880 Protein, Trx1 Protein, Txn Protein, trx Protein, TXN Protein, SCM1.18 Protein, trxA3 Protein, thioredoxin Protein, TR-1 Protein, Trx-1 Protein, thioredoxin Protein, thioredoxin 1 Protein, thioredoxin L homeolog Protein, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) Protein, thioredoxin pseudogene Protein, cytosolic thioredoxin Trx1 Protein, TXN Protein, Txn1 Protein, txn.L Protein, txn Protein, trx Protein, SCO0885 Protein, PHG25ORF099c Protein, LOC100349046 Protein, Txn Protein, trx1 Protein
    Background
    Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Ref.16 Ref.18 Ref.19 Ref.21 Ref.24 ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). Synonyms: Short name=Trx Alternative name(s): ATL-derived factor Short name=ADF Surface-associated sulphydryl protein Short name=SASP.
    Molecular Weight
    39 kD
    NCBI Accession
    NM_003329
    UniProt
    P10599
    Pathways
    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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