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CD200R1 Protein (AA 26-238) (hIgG-His-tag)

Recombinant CD200R1 protein expressed in Baculovirus infected Insect Cells.
Catalog No. ABIN6387907
$847.69
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Quick Overview for CD200R1 Protein (AA 26-238) (hIgG-His-tag) (ABIN6387907)

Target

See all CD200R1 Proteins
CD200R1 (CD200 Receptor 1 (CD200R1))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 19
  • 6
  • 1
  • 1
  • 1
  • 1
Mouse

Source

  • 17
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Baculovirus infected Insect Cells

Application

SDS-PAGE (SDS), Activity Assay (AcA)

Purity

> 95 %
  • Protein Characteristics

    AA 26-238

    Purification tag / Conjugate

    This CD200R1 protein is labelled with hIgG-His-tag.

    Sequence

    TDKNQTT QNNSSSPLTQ VNTTVSVQIG TKALLCCFSI PLTKAVLITW IIKLRGLPSC TIAYKVDTKT NETSCLGRNI TWASTPDHSP ELQISAVTLQ HEGTYTCETV TPEGNFEKNY DLQVLVPPEV TYFPEKNRSA VCEAMAGKPA AQISWSPDGD CVTTSESHSN GTVTVRSTCH WEQNNVSDVS CIVSHLTGNQ SLSIELSRGG NQSLRP

    Purification

    > 95% by SDS-PAGE

    Endotoxin Level

    < 1 EU per 1ug of protein (determined by LAL method)

    Biological Activity Comment

    Measured by its binding ability in a functional ELISA with Mouse CD200 (CAT# ATGP3964). The ED50 range ≤ 1 ug/ml.
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • Target

    CD200R1 (CD200 Receptor 1 (CD200R1))

    Alternative Name

    CD200R1

    Background

    Cd200r1, also known cell surface glycoprotein CD200 receptor 1, is an isoform of CD200 receptors which is expressed on cells of the myeloid lineage. Its inhibitory signaling pathway has been implicated in playing a prominent role in limiting inflammation in a wide range of inflammatory diseases. Its signaling inhibits the expression of proinflammatory molecules including tumor necrosis factor, interferons, and inducible nitric oxide synthase in response to selected stimuli. Recombinant mouse Cd200r1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    Molecular Weight

    50.4 kDa (455aa)

    NCBI Accession

    NP_067300
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