BTN3A1 Protein (AA 30-254) (hIgG-His-tag)
Quick Overview for BTN3A1 Protein (AA 30-254) (hIgG-His-tag) (ABIN6388072)
Target
See all BTN3A1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 30-254
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Purification tag / Conjugate
- This BTN3A1 protein is labelled with hIgG-His-tag.
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Sequence
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QFSVLGPSGP ILAMVGEDAD LPCHLFPTMS AETMELKWVS SSLRQVVNVY ADGKEVEDRQ SAPYRGRTSI LRDGITAGKA ALRIHNVTAS DSGKYLCYFQ DGDFYEKALV ELKVAALGSD LHVDVKGYKD GGIHLECRST GWYPQPQIQW SNNKGENIPT VEAPVVADGV GLYAVAASVI MRGSSGEGVS CTIRSSLLGL EKTASISIAD PFFRSAQRWI AALAG
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Purification
- > 90% by SDS-PAGE
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
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Alternative Name
- CD277/BTN3A1
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Background
- BTN3A1, also known as butyrophilin subfamily 3 member A1 isoform, belongs to the immunoglobulin superfamily. It is composed of an extracellular N-terminal IgV and a membrane proximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. This protein plays a role in T-cell activation and in the adaptive immune response. Also, it regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Recombinant human BTN3A1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 51.1 kDa (464aa)
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NCBI Accession
- NP_008979
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Pathways
- Activated T Cell Proliferation
Target
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