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BTN3A1 Protein (Biotin)

BTN3A1 Origin: Human Host: Human Cells Recombinant >90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319892
  • Target See all BTN3A1 Proteins
    BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
    Protein Type
    Recombinant
    Origin
    • 14
    • 3
    Human
    Source
    • 12
    • 3
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This BTN3A1 protein is labelled with Biotin.
    Purpose
    Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated
    Sequence
    Gln30-Gly254
    Characteristics
    Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.
    Purity
    >90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product BTN3A1 Protein
  • Comment

    58-62 kDa

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
    Alternative Name
    BTN3A1 (BTN3A1 Products)
    Synonyms
    BT3.1 Protein, BTF5 Protein, CD277 Protein, BTN3A1 Protein, butyrophilin subfamily 3 member A1 Protein, BTN3A1 Protein, LOC100447925 Protein
    Background

    Background: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.

    Synonym: Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5

    Molecular Weight
    52.6 kDa
    UniProt
    O00481
    Pathways
    Activated T Cell Proliferation
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