SNCA Protein (A30P, A53T, AA 1-140)
Quick Overview for SNCA Protein (A30P, A53T, AA 1-140) (ABIN666813)
Target
See all SNCA ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- A30P, A53T, AA 1-140
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Sequence
- MDVFMKGLSK AKEGVVAAAE KTKQGVAEAP GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
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Characteristics
- alpha-Synuclein A30P/A53T, Human, Recombinant, E.coli
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Purification
- > 95% by SDS-PAGE
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Synuclein, alpha (SNCA) (A53T) (Active) protein
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (active) proteinSNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Synuclein, alpha (SNCA) proteinSNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (His-IF2DI Tag)SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) proteinSNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 7.5) containing 0.1M NaCl
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- SNCA (Synuclein, alpha (SNCA))
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Alternative Name
- alpha-Synuclein
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Background
- A Parkinson's disease-related double mutant (A30P/A53T) of alpha-synuclein. The recombinant protein was purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques
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Molecular Weight
- 14.5 kDa (140aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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NCBI Accession
- NP_000336
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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