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SMAD3 Protein (AA 1-425) (His tag)

SMAD3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN666909
  • Target See all SMAD3 Proteins
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-425
    Origin
    • 13
    • 4
    • 3
    • 1
    • 1
    Human
    Source
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SMAD3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    SMAD3, 1-425 aa, Human, His-tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SMAD3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl and 1 mM DTT
    Storage
    4 °C
  • Target
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    Alternative Name
    SMAD3 (SMAD3 Products)
    Synonyms
    HSPC193 Protein, HsT17436 Protein, JV15-2 Protein, LDS1C Protein, LDS3 Protein, MADH3 Protein, madh3 Protein, madh3a Protein, smad3 Protein, wu:fa99e03 Protein, XSmad3 Protein, XenMLP Protein, Xmad3 Protein, madh3-A Protein, Madh3 Protein, AU022421 Protein, Smad 3 Protein, mad3 Protein, madh3b Protein, zgc:92234 Protein, SMAD family member 3 Protein, SMAD family member 3a Protein, SMAD family member 3 L homeolog Protein, SMAD family member 3b Protein, SMAD3 Protein, smad3a Protein, smad3.L Protein, Smad3 Protein, smad3b Protein
    Background
    SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases. Recombinant SMAD3 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HSPC193, HsT17436, JV15-2, MADH3, Mothers against decapentaplegic homolog 3 DKFZP586N0721, DKFZp686J10186, hMAD 3, hSMAD3, MAD (mothers against decapentaplegic Drosophila) homolog 3, HST17436, JV15 2, JV152, MAD3, MADH 3, MGC60396, Mothers against DPP homolog 3, SMA and MAD related protein 3, SMAD, SMAD 3, SMAD3,. NCBI no.: NP_005893
    Molecular Weight
    50.2 kDa (445aa), confirmed by MALDI-TOF.
    Pathways
    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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