SKP1 Protein (AA 1-160)
Quick Overview for SKP1 Protein (AA 1-160) (ABIN666914)
Target
See all SKP1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-160
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Sequence
- MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL
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Characteristics
- SKP1, 1- 160aa, Human, E.coli
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Purification
- > 90% by SDS-PAGE
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S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-160) protein (GST tag)
SKP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-160) proteinSKP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
S-Phase Kinase-Associated Protein 1 (SKP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)SKP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
S-Phase Kinase-Associated Protein 1 (SKP1) (AA 2-163) protein (GST tag)SKP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 50 mM NaCl, 10 % glycerol
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
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Alternative Name
- SKP1
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Background
- S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 18 kDa (160aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_008861
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Pathways
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
Target
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