Calmodulin 2 Protein (CALM2) (AA 1-149)

Catalog No. ABIN667070

This Recombinant Calmodulin 2 protein is produced in Escherichia coli (E. coli).

Quick Overview for Calmodulin 2 Protein (CALM2) (AA 1-149) (ABIN667070)

Target: Calmodulin 2 (CALM2)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 1-149

Sequence: MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK

Characteristics: Calmodulin 2, 1-149aa, Human , Recombinant, E.coli

Purification: > 90% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 7.5)

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Calmodulin 2 (CALM2)

Alternative Name: Calmodulin 2/CALM2

Background: Calmodulin has been known to act as an intracellular calcium sensor protein. When the intracellular Ca2+ concentration increases, calmodulin can bind up to four Ca2+, changing its conformation and regulating cellular functions such as activation or inhibition of a large number of enzymes, ion channels, and receptors. Recombinant human Calmodulin was expressed in E. coli and purified by conventional chromatography techniques.

Molecular Weight: 16 kDa (149aa) confirmed by MALDI-TOF

NCBI Accession: NP_001734

Pathways: RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cellular Glucan Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Phototransduction, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals, BCR Signaling