SNCA Protein (AA 1-140)
Quick Overview for SNCA Protein (AA 1-140) (ABIN667142)
Target
See all SNCA ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-140
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Sequence
- MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA
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Characteristics
- SNCA, 1-140aa, Mouse, E.coli
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Purification
- > 95% by SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 7.5) containing, 10 % glycerol
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- SNCA (Synuclein, alpha (SNCA))
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Alternative Name
- alpha-Synuclein
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Background
- Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. Recombinant mouse alpha-Synuclein, was expressed in E. coli and purified by using conventional chromatography techniques
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Molecular Weight
- 14.4 kDa (140aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_033247
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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