PVRIG Protein (AA 41-171) (Fc Tag)
Quick Overview for PVRIG Protein (AA 41-171) (Fc Tag) (ABIN6809885)
Target
See all PVRIG ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 41-171
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Purification tag / Conjugate
- This PVRIG protein is labelled with Fc Tag.
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Sequence
- AA 41-171
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
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Alternative Name
- PVRIG
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Background
- Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3 % similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
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Molecular Weight
- 40.1 kDa
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NCBI Accession
- XP_005549281
Target
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