PVRIG Protein (AA 41-171) (Fc Tag)
-
- Target See all PVRIG Proteins
- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 41-171
-
Origin
- Cynomolgus
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PVRIG protein is labelled with Fc Tag.
- Sequence
- AA 41-171
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PVRIG Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
-
- Target
- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
- Alternative Name
- PVRIG (PVRIG Products)
- Synonyms
- C7orf15 Protein, PVR related immunoglobulin domain containing Protein, PVRIG Protein
- Background
- Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3 % similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
- Molecular Weight
- 40.1 kDa
- NCBI Accession
- XP_005549281
-