SIGLEC15 Protein (AA 20-263) (His tag)
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- Target See all SIGLEC15 Proteins
- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-263
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIGLEC15 protein is labelled with His tag.
- Sequence
- AA 20-263
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SIGLEC15 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 25 mM MES, 150 mM NaCl, pH 5.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
- Alternative Name
- Siglec-15 (SIGLEC15 Products)
- Synonyms
- RGD1565948 Protein, CD33L3 Protein, HsT1361 Protein, SIGLEC-15 Protein, Cd33l3 Protein, EG620235 Protein, SIGLEC-I Protein, sialic acid binding Ig-like lectin 15 Protein, sialic acid binding Ig like lectin 15 Protein, Siglec15 Protein, SIGLEC15 Protein
- Background
- Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
- Molecular Weight
- 28.4 kDa
- NCBI Accession
- NP_998767
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