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CD27 Protein (AA 20-191) (mFc-His Tag)

CD27 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Catalog No. ABIN6961086
  • Target See all CD27 Proteins
    CD27 (CD27 Molecule (CD27))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-191
    Origin
    • 26
    • 9
    • 3
    • 3
    • 1
    Human
    Source
    • 20
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD27 protein is labelled with mFc-His Tag.
    Application
    ELISA
    Purpose
    Recombinant human CD27 protein with C-terminal mouse Fc and 6xHis tag
    Specificity
    CD27 (Ala20-Arg191) mFc (Pro99-Lys330) 6xHis
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CD27 (CD27 Molecule (CD27))
    Alternative Name
    CD27 (CD27 Products)
    Background
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
    Molecular Weight
    predicted molecular mass of 65-72 kDa after removal of the signal peptide.
    Gene ID
    939
    UniProt
    P26842
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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