SIGLEC15 Protein (AA 20-263) (His tag,mFc Tag)
Quick Overview for SIGLEC15 Protein (AA 20-263) (His tag,mFc Tag) (ABIN6961145)
Target
See all SIGLEC15 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 20-263
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Purification tag / Conjugate
- This SIGLEC15 protein is labelled with His tag,mFc Tag.
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Purpose
- Recombinant human SIGLEC15 protein with C-terminal mouse Fc and 6xHis tag
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Specificity
- SIGLEC15(Phe20-Thr263) mFc(Pro99-Lys330) 6xHis tag
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 60-322) (Active) protein (His-Avi Tag)
SIGLEC15 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 20-263) (Active) protein (His-Avi Tag)SIGLEC15 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 60-322) (Active) protein (Biotin,His-Avi Tag)SIGLEC15 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (mFc Tag)SIGLEC15 Origin: Human Host: Human Cells Recombinant >90 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (His tag)SIGLEC15 Origin: Cynomolgus Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (His tag)SIGLEC15 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (Fc Tag)SIGLEC15 Origin: Cynomolgus Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (Fc Tag)SIGLEC15 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 24-260) (Active) protein (hFc Tag)SIGLEC15 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 24-262) (Active) protein (Biotin,His tag)SIGLEC15 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
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Alternative Name
- SIGLEC15
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Background
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CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15
SIGLEC15 (Sialic Acid Binding Ig Like Lectin 15) is a Protein Coding gene. Diseases associated with SIGLEC15 include Osteoporosis,Juvenile and Osteoporosis. Among its related pathways are Innate Immune System and RET signaling. An important paralog of this gene is SIGLEC1. -
Molecular Weight
- predicted molecular mass of 53.6 kDa after removal of the signal peptide.The apparent molecular mass of SIGLEC15-mFc-His is 55-70 kDa due to glycosylation.
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Gene ID
- 284266
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UniProt
- Q6ZMC9
Target
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