PVRIG Protein (AA 99-330) (Fc Tag)
Quick Overview for PVRIG Protein (AA 99-330) (Fc Tag) (ABIN6964111)
Target
See all PVRIG ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 99-330
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Purification tag / Conjugate
- This PVRIG protein is labelled with Fc Tag.
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Purpose
- Recombinant human PVRIG protein with C-terminal human Fc tag
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Specificity
- PVRIG(Met1-Thr25 Pro80-Ala170) hFc(Glu99-Ala330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (hFc Tag)
PVRIG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 1-326) protein (His tag)custom-made PVRIG Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (Active) protein (mFc Tag)PVRIG Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) (Active) protein (hFc-Avi Tag)PVRIG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) (Active) protein (hFc-Avi Tag,Biotin)PVRIG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) protein (DYKDDDDK Tag)PVRIG Origin: Human Host: HEK-293 Cells Synthetic Nanodisc ELISA, Imm, cryo-EM, PhD, SPR
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) protein (His tag)PVRIG Origin: Cynomolgus Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 38-326) protein (GST tag)PVRIG Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
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Alternative Name
- PVRIG
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Background
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C7orf15,CD112R
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function] -
Molecular Weight
- predicted molecular mass of 38.2 kDa after removal of the signal peptide.The apparent molecular mass of PVRIG-hFc is 55-70 kDa due to glycosylation.
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Gene ID
- 79037
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UniProt
- Q6DKI7
Target
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