HGF Protein (AA 32-728) (Fc Tag)
Quick Overview for HGF Protein (AA 32-728) (Fc Tag) (ABIN6992334)
Target
See all HGF ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 32-728
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Purification tag / Conjugate
- This HGF protein is labelled with Fc Tag.
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Purpose
- Human HGF Protein, Fc Tag (MALS verified)
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
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Storage
- -20 °C
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- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
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Alternative Name
- HGF
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Background
- Hepatocyte growth factor (HGF) is a paracrine cellular growth, motility and morphogenic factor. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. In addition, HGF has been implicated in a variety of cancers, including of the lungs, pancreas, thyroid, colon, and breast.
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Molecular Weight
- 106.1 kDa
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NCBI Accession
- NP_000592
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Pathways
- RTK Signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
Target
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