HGF Protein (AA 32-285)
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- Target See all HGF Proteins
- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-285
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MQRKRRNTIH EFKKSAKTTL IKIDPALKIK TKKVNTADQC ANRCTRNKGL PFTCKAFVFD KARKQCLWFP FNSMSSGVKK EFGHEFDLYE NKDYIRNCII GKGRSYKGTV SITKSGIKCQ PWSSMIPHEH SYRGKDLQEN YCRNPRGEEG GPWCFTSNPE VRYEVCDIPQ CSEVECMTCN GESYRGLMDH TESGKICQRW DHQTPHRHKF LPERYPDKGF DDNYCRNPDG QPRPWCYTLD PHTRWEYCAI KTCET
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product HGF Protein
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Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 32-728) protein (His tag)
HGF Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 32-728) protein (Fc Tag)HGF Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 32-494), (AA 495-728) (Active) proteinHGF Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 32-124) protein (GST tag)HGF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 477-728) protein (His tag)HGF Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 496-728) protein (His-IF2DI Tag)HGF Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 493-721) protein (His-IF2DI Tag)HGF Origin: Chicken Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 619-728) protein (GST tag)HGF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
- Alternative Name
- HGF (HGF Products)
- Synonyms
- DFNB39 Protein, F-TCF Protein, HGFB Protein, HPTA Protein, SF Protein, HGF Protein, C230052L06Rik Protein, HGF/SF Protein, NK1 Protein, NK2 Protein, SF/HGF Protein, hepatocyte growth factor Protein, HGF Protein, Hgf Protein
- Background
- Hepatocyte growth factor(HGF) regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69- kDa alpha-chain and 34- kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Recombinant human HGF protein was expressed in E.coli .
- Molecular Weight
- 29.8 kDa (255aa)
- NCBI Accession
- NP_001010933
- UniProt
- P14210
- Pathways
- RTK Signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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