SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (His tag)

Catalog No. ABIN6992361

This Recombinant SARS-CoV-2 Spike S1 protein is produced in HEK-293 Cells.

Quick Overview for SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (His tag) (ABIN6992361)

Target: SARS-CoV-2 Spike S1

Protein Type: Recombinant

Biological Activity: Active

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma

Source: HEK-293 Cells

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: P.1 - gamma

Purification tag / Conjugate: This SARS-CoV-2 Spike S1 protein is labelled with His tag.

Purpose: SARS-CoV-2 S1 protein (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y), His Tag

Sequence: AA 16-685

Characteristics: SARS-CoV-2 S1 protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y mutations were identified in the SARS-CoV-2 variant (known as P.1 lineage) which emerged in Brazil.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: SARS-CoV-2 Spike S1

Alternative Name: SARS-CoV-2 S1 protein

Target Type: Viral Protein

Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molecular Weight: 76.9 kDa