IL-2 R beta & IL-2 R gamma (AA 27-239) (Active) protein (His tag,Strep Tag)

Catalog No. ABIN6992422

This Recombinant IL-2 R beta & IL-2 R gamma protein is expressed in HEK-293 Cells.

Quick Overview for IL-2 R beta & IL-2 R gamma (AA 27-239) (Active) protein (His tag,Strep Tag) (ABIN6992422)

Target: IL-2 R beta & IL-2 R gamma

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: >95 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 27-239

Purification tag / Conjugate: His tag,Strep Tag

Purpose: Human IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: IL-2 R beta & IL-2 R gamma

Background: Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Molecular Weight: 29.9 kDa, 34.1 kDa