IL-2 R beta & IL-2 R gamma (AA 27-239) (Active) protein (Fc Tag)

Catalog No. ABIN7013496

This Recombinant IL-2 R beta & IL-2 R gamma protein is produced in HEK-293 Cells.

Quick Overview for IL-2 R beta & IL-2 R gamma (AA 27-239) (Active) protein (Fc Tag) (ABIN7013496)

Target: IL-2 R beta & IL-2 R gamma

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: >95 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 27-239

Purification tag / Conjugate: Fc Tag

Characteristics: Human IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: MALS verified

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: IL-2 R beta & IL-2 R gamma

Sub Type: Cocktail

Background: Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Molecular Weight: 51.1 kDa (IL-2RB) and 53.6 kDa (IL-2RG)