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IL-2 R beta & IL-2 R gamma (AA 27-239) protein (His tag,Twin-Strep tag)

Origin: Rat Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7013081
  • Target
    IL-2 R beta & IL-2 R gamma
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-239
    Origin
    • 4
    • 2
    • 2
    Rat
    Source
    • 8
    HEK-293 Cells
    Purification tag / Conjugate
    His tag,Twin-Strep tag
    Purpose
    Rat IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    IL-2 R beta & IL-2 R gamma
    Background
    Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
    Molecular Weight
    30.2 kDa | 34.7 kDa
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