SARS-CoV Spike Protein (AA 14-1195) (His tag)
Quick Overview for SARS-CoV Spike Protein (AA 14-1195) (His tag) (ABIN7013276)
Target
See all SARS-CoV Spike (SARS-CoV S) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
-
-
Protein Characteristics
- AA 14-1195
-
Purification tag / Conjugate
- This SARS-CoV Spike protein is labelled with His tag.
-
Sequence
- AA 14-1195
-
Characteristics
- SARS S protein (R667A, K968P, V969P), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP13567.1(R667A, K968P, V969P). The recombinant protein is expressed with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (K968P, V969P) and alanine substitutions (R667A) are introduced to stabilize the trimeric prefusion state of SARS-CoV S protein and abolish the furin cleavage site, respectively.
-
Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
SARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (His-Avi Tag)
SARS-CoV S Origin: SARS Coronavirus (SARS-CoV) Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (His tag)SARS-CoV S Origin: SARS Coronavirus (SARS-CoV) Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE.
> 95 % as determined by SEC-MALS. ELISA, SDSSARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (His-Avi Tag,Biotin)SARS-CoV S Origin: SARS Coronavirus (SARS-CoV) Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (mFc Tag)SARS-CoV S Origin: SARS Coronavirus (SARS-CoV) Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE.
-
-
Application Notes
- MALS verified
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- PBS
-
Storage
- -20 °C
-
-
- SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
-
Alternative Name
- SARS S protein
-
Target Type
- Viral Protein
-
Background
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
-
Molecular Weight
- 136.3 kDa
Target
-
