Glucagon Receptor Protein (GCGR) (AA 26-136) (His tag)

Catalog No. ABIN7013755

This Recombinant Glucagon Receptor protein is produced in HEK-293 Cells.

Quick Overview for Glucagon Receptor Protein (GCGR) (AA 26-136) (His tag) (ABIN7013755)

Target: Glucagon Receptor (GCGR)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 26-136

Purification tag / Conjugate: This Glucagon Receptor protein is labelled with His tag.

Characteristics: Human GCGR / Glucagon receptor Protein, His Tag (MALS verified)

Endotoxin Level: Less than 0.1 EU per μg by the LAL method.

Application Details

Application Notes: MALS verified

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: Glucagon Receptor (GCGR)

Alternative Name: GCGR

Background: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

Molecular Weight: 14.9 kDa

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process