Glucagon Receptor Protein (GCGR) (Biotin,His-Avi Tag)
MALS verified
GCGR
Origin: Human
Host: HEK-293 Cells
Recombinant
90,00 %
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- Target See all Glucagon Receptor (GCGR) Proteins
- Glucagon Receptor (GCGR)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Glucagon Receptor protein is labelled with Biotin,His-Avi Tag.
- Purpose
- Biotinylated Human GCGR / Glucagon receptor Protein, His,Avitag™ (MALS verified)
- Sequence
- Ala 26 - Lys 136
- Characteristics
- Biotinylated Human GCGR / Glucagon receptor, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Lys 136 (Accession # P47871-1).
- Purity
- 90,00 %
- Endotoxin Level
- 1.0 EU per μg
- Grade
- MALS verified
- Top Product
- Discover our top product GCGR Protein
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Glucagon Receptor (GCGR) (AA 26-136) protein (His tag)
GCGR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- Comment
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 16.6 kDa. The protein migrates as 27-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- Glucagon Receptor (GCGR)
- Alternative Name
- GCGR (GCGR Products)
- Synonyms
- GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
- Background
- Synonyms:Glucagon R, GCGR,Glucagon receptor,Description:G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
- Molecular Weight
- 16.6 kDa
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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