CCR5 Protein-VLP
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- Target See all CCR5 Proteins
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Protein Type
- VLP
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CCR5 Full Length Protein-VLP (HEK293)
- Sequence
- Met 1 - Leu 352
- Characteristics
- Human CCR5 Full Length Protein-VLP (CC5-H52P3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 352 (Accession # P51681-1).
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CCR5 Protein
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Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) protein (Strep Tag)
Crystallography grade CCR5 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) protein (GST tag)CCR5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 2-223), (AA 227-319) (Active) protein (His tag,DYKDDDDK Tag)CCR5 Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
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- Application Notes
- The protein has a calculated MW of 40.5 kDa.
- Comment
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Virus-like particles (VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrance Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C
- Storage Comment
- -70°C
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- Target
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Alternative Name
- CCR5 (CCR5 Products)
- Synonyms
- CC-CKR-5 Protein, CCCKR5 Protein, CCR-5 Protein, CD195 Protein, CKR-5 Protein, CKR5 Protein, CMKBR5 Protein, IDDM22 Protein, Ckr5 Protein, Cmkbr5 Protein, CCR1-L Protein, GPCR Protein, CCR5 Protein, AM4-7 Protein, C-C motif chemokine receptor 5 (gene/pseudogene) Protein, chemokine (C-C motif) receptor 5 Protein, C-C motif chemokine receptor 5 Protein, CCR5 Protein, Ccr5 Protein
- Background
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Synonyms: CCR5,CMKBR5,CD195,CC-CKR-5,CHEMR13,
Description: Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1. - Molecular Weight
- 40.5 kDa
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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