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CCR5 Protein (AA 2-223, AA 227-319) (His tag,DYKDDDDK Tag)

CCR5 Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Catalog No. ABIN7013588
  • Target See all CCR5 Proteins
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 2-223, AA 227-319
    Origin
    • 8
    • 4
    • 2
    • 1
    Human
    Source
    • 5
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CCR5 protein is labelled with His tag,DYKDDDDK Tag.
    Characteristics
    Human CCR5 Protein, Flag,His Tag
    Purity
    >85 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CCR5 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5
    Storage
    -80 °C
  • Target
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Alternative Name
    CCR5 (CCR5 Products)
    Synonyms
    CC-CKR-5 Protein, CCCKR5 Protein, CCR-5 Protein, CD195 Protein, CKR-5 Protein, CKR5 Protein, CMKBR5 Protein, IDDM22 Protein, Ckr5 Protein, Cmkbr5 Protein, CCR1-L Protein, GPCR Protein, CCR5 Protein, AM4-7 Protein, C-C motif chemokine receptor 5 (gene/pseudogene) Protein, chemokine (C-C motif) receptor 5 Protein, C-C motif chemokine receptor 5 Protein, CCR5 Protein, Ccr5 Protein
    Background
    Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
    Molecular Weight
    46.0 kDa
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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