ADAM17 Protein (AA 752-824) (His-IF2DI Tag)

Catalog No. ABIN7121690

This Recombinant ADAM17 protein is produced in Escherichia coli (E. coli).

Quick Overview for ADAM17 Protein (AA 752-824) (His-IF2DI Tag) (ABIN7121690)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB), ELISA

Purity: Greater than 90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 752-824

Purification tag / Conjugate: This ADAM17 protein is labelled with His-IF2DI Tag.

Purpose: Recombinant Human ADAM17

Sterility: 0.2 μm filtered

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/mL by gently pipetting 2-3 times, don't vortex.

Buffer: Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5 % trehalose, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.

Expiry Date: 12 months

Target Details

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name: ADAM17

Background: ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, ADAM17, ADAM18, CD156b antigen, CD156b, CSVP, disintegrin and metalloproteinase domain-containing protein 17, EC 3.4.24.86, MGC71942, Snake venom-like protease, TACE, TACEcSVP

Molecular Weight: 29 kDa

UniProt: P78536

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus