JAK2 Protein (AA 241-351) (His-IF2DI Tag)
Quick Overview for JAK2 Protein (AA 241-351) (His-IF2DI Tag) (ABIN7123645)
Target
See all JAK2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 241-351
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Purification tag / Conjugate
- This JAK2 protein is labelled with His-IF2DI Tag.
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Purpose
- Recombinant Human JAK2
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Sterility
- 0.2 μm filtered
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Janus Kinase 2 (JAK2) (AA 1-1132) protein (His tag)
custom-made JAK2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Janus Kinase 2 (JAK2) (AA 1014-1132) protein (His tag)JAK2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/mL by gently pipetting 2-3 times, don't vortex.
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Buffer
- Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5 % trehalose, pH 7.4.
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Storage
- -20 °C,-80 °C
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Storage Comment
- The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.
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Expiry Date
- 12 months
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- JAK2 (Janus Kinase 2 (JAK2))
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Alternative Name
- JAK2
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Background
- JAK 2, JAK-2, JAK2, JAK2_HUMAN, Janus Activating Kinase 2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, OTTHUMP00000043260, THCYT3, Tyrosine protein kinase JAK2, Tyrosine-protein kinase JAK2
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Molecular Weight
- 33 kDa
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UniProt
- O60674
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Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
Target
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