AKR1C2 Protein
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- Target See all AKR1C2 Proteins
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human AKR1C2 Protein
- Sequence
- Met 1-Tyr323
- Characteristics
- Recombinant Human Aldo-Keto Reductase Family 1 Member C2 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AKR1C2 Protein
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Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-256) protein (His tag)
AKR1C2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) protein (GST tag)AKR1C2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 224-323) protein (GST tag)AKR1C2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) protein (Strep Tag)Crystallography grade AKR1C2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323), (full length) protein (His-SUMO Tag)AKR1C2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) protein (Myc-DYKDDDDK Tag)AKR1C2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Alternative Name
- AKR1C2 (AKR1C2 Products)
- Synonyms
- AKR1C-pseudo Protein, BABP Protein, DD Protein, DD2 Protein, DDH2 Protein, HAKRD Protein, HBAB Protein, MCDR2 Protein, SRXY8 Protein, Akr1c21 Protein, aldo-keto reductase family 1 member C2 Protein, aldo-keto reductase family 1, member C2 Protein, AKR1C2 Protein, Akr1c2 Protein
- Background
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Background: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
Synonym: Aldo-Keto Reductase Family 1 Member C2, 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, Dihydrodiol Dehydrogenase 2, DD-2, DD2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, DD/BABP, Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase, Type III 3-Alpha-Hydroxysteroid Dehydrogenase, AKR1C2, DDH2
- Molecular Weight
- 36.7 kDa
- UniProt
- P52895
- Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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