AKR1C2 Protein (AA 1-323, full length) (His-SUMO Tag)
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- Target See all AKR1C2 Proteins
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-323
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AKR1C2 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEAVKL AIEAGFHHID SAHVYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA MEKCKDAGLA KSIGVSNFNH RLLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product AKR1C2 Protein
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Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-256) protein (His tag)
AKR1C2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) protein (GST tag)AKR1C2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 224-323) protein (GST tag)AKR1C2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) protein (Strep Tag)Crystallography grade AKR1C2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) protein (Myc-DYKDDDDK Tag)AKR1C2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Alternative Name
- AK1C2 (AKR1C2 Products)
- Synonyms
- AKR1C-pseudo Protein, BABP Protein, DD Protein, DD2 Protein, DDH2 Protein, HAKRD Protein, HBAB Protein, MCDR2 Protein, SRXY8 Protein, Akr1c21 Protein, aldo-keto reductase family 1 member C2 Protein, aldo-keto reductase family 1, member C2 Protein, AKR1C2 Protein, Akr1c2 Protein
- Background
- Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
- Molecular Weight
- 52.7 kDa
- UniProt
- P52895
- Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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