ALAS2 Protein (AA 2-527)

Catalog No. ABIN7319672

Recombinant ALAS2 protein expressed in Escherichia coli (E. coli).

Quick Overview for ALAS2 Protein (AA 2-527) (ABIN7319672)

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 2-527

Purpose: Recombinant Human Catalase/CAT Protein

Sequence: Ala2-Leu527

Characteristics: Recombinant Human Catalase is produced by our E.coli expression system and the target gene encoding Ala2-Leu527 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Alternative Name: alase

Background: MGC138422,MGC138424,Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase is localized in the peroxisome. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells, and normal and transformed fibroblast cells. Defects in CAT are the cause of acatalasemia which is characterized by absence of catalase activity in red cells and is associated with ulcerating oral lesions.

Molecular Weight:

Calculated MW: 59.7 kDa

Observed MW: 60 kDa

Gene ID: 847

UniProt: P04040

Pathways: Transition Metal Ion Homeostasis