BTN1A1 Protein (His tag)

Catalog No. ABIN7318211

This Recombinant BTN1A1 protein is expressed in Human Cells.

Quick Overview for BTN1A1 Protein (His tag) (ABIN7318211)

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This BTN1A1 protein is labelled with His tag.

Purpose: Recombinant Human Butyrophilin 1A1/BTN1A1 Protein (His Tag)

Sequence: Ala27-Arg242

Characteristics: Recombinant Human Butyrophilin Subfamily 1 Member A1 is produced by our Mammalian expression system and the target gene encoding Ala27-Arg242 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Alternative Name: Butyrophilin 1A1/BTN1A1

Background:

Background: Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Synonym: Butyrophilin Subfamily 1 Member A1, BT, BTN1A1, BTN

Molecular Weight: 25.0 kDa

UniProt: Q13410

Pathways: Activated T Cell Proliferation