Cathepsin B Protein (CTSB) (His tag)
Quick Overview for Cathepsin B Protein (CTSB) (His tag) (ABIN7318252)
Target
See all Cathepsin B (CTSB) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Cathepsin B protein is labelled with His tag.
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Purpose
- Recombinant Human Cathepsin B/CTSB Protein (His Tag)
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Sequence
- Arg18-Ile339
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Characteristics
- Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Cathepsin B (CTSB) protein (His tag)
CTSB Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin B (CTSB) (AA 1-339) protein (GST tag)CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin B (CTSB) (AA 21-339) protein (GST tag)CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Cathepsin B (CTSB) (Active) protein (His tag)CTSB Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Cathepsin B (CTSB) (AA 18-339) (Active) protein (His tag)CTSB Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
Cathepsin B (CTSB) protein (His tag)CTSB Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin B (CTSB) (AA 82-333), (partial) protein (GST tag)CTSB Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Cathepsin B (CTSB)
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Alternative Name
- Cathepsin B/CTSB
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Background
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Background: Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
Synonym: Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB
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Molecular Weight
- 36.9 kDa
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UniProt
- P07858
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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